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BOX 1 The immunobiology of MS The immune-mediated biology of MS identifies a prominent role of peripherally-derived T and B cells in acute active demyelinating lesions, with microglia, macrophages and astrocytes mainly responsible for chronic inflammation (Rodrguez Mura et al., 2022
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Reconstitution Steps Draw 1.0 mL bacteriostatic water with a sterile syringe
In 2009, an oxyntomodulin-based multi-agonist peptide with glucagon and GLP-1 agonistic actions were created
Scientific References Cobalin-H 1000 microgram/ml Injection (SmPC)
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