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The carcinogenic risk of GLP-1RAs remains controversial: large-scale cohort studies have not identified an association with pancreatic cancer 36 , but animal experiments suggest that long-term high-dose use may induce ductal hyperplasia 37,38

Nature 372:425432 Heymsfield SB, Greenberg AS, Fujioka K et al (1999) Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

Berberine on the prevention and management of cardiometabolic disease: clinical applications and mechanisms of action

It wasn't until I [went] on Mounjaro and realized it's a chronic disease

(NIDDK) Brain pathways involved in hunger and cravings are altered in a way that reduces appetite

Therefore, GLP-1RAs appear to have a beneficial role in the treatment of POCS