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The placebo-controlled SURMOUNT-OSA trial evaluated Zepbound for the treatment of moderate to severe OSA in adults with obesity, without type 2 diabetes mellitus (T2DM)

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Recombinant human GLP-1 inhibits protein kinase C (PKC)-, but increases protein kinase A (PKA), which reduces oxidative stress in both glomeruli and tubules (Yin et al., 2019)

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