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The thyroid gland is uniquely vulnerable to oxidative stress - it generates hydrogen peroxide as an unavoidable byproduct of hormone synthesis, making robust antioxidant protection not a luxury but a biological necessity

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A recent study found that TIGIT+CCR7- Tregs, which correlated positively with cell function, secrete high levels of TGF-1, acting as a potent immunosuppressive signaling specifically targeting and inhibiting the functional activity of cytotoxic CD226+CCR7- CD8+ T cells in mice (97)

Tumor Necrosis Factor Alpha Blockade and Multiple Sclerosis: Exploring New Avenues

Oanh NTK, Lee HS, Kim YH, Min S, Park YJ, Heo J et al (2022) Regulation of nuclear DNA damage response by mitochondrial morphofunctional pathway

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