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Because HepG2 cells are highly de-differentiated compared to normal hepatocytes in situ, and therefore are expected to have a less robust Met cycle and transsulfuration pathway than those found in normal liver, the GSH pool in normal liver could contain a substantially larger proportion of Met-derived S [115, 116, 118120]

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TLDR GHK Cu is a naturally occurring complex of the tripeptide GHK and a copper ion

The Effects of Curcumin on Serum Heat Shock Protein 27 Antibody Titers in Patients with Metabolic Syndrome