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Although there is no clinical trial underway specifically evaluating the safety and efficacy of combination therapy of BRAF inhibitor plus MEK inhibitor in MM, a retrospective study in Japan showed that MM/AM and CM exhibited similar response rates to combined BRAF and MEK suppression (64.3% vs 76.5%) (139), suggesting the potential efficiency of dual repression of BRAF and MEK in MM

This injectable form of Vitamin B12 may be given subcutaneously (subQ, under the skin) or intramuscularly (IM, into the muscle)

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De aller fleste av studiedeltakerne fortsatte g ned i vekt, om enn i noe roligere tempo etter de frste 12 ukene

Compliance to the supplementation protocol was monitored by the research dietician who contacted participants on a weekly basis by phone