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Reason for caution: GLP-1 receptors are present in thyroid C-cells

p -values below 0.05 ( ), 0.01 (#), and 0.001 () were considered as significant

Eli Lillys Phase 3 Ofroglipron trial suggests it may help a person feel full faster, eat less, and slowly digest food, potentially supporting weight loss

samples were then deproteinized by adding an equal volume of metaphosphoric acid (5%) on ice for 10 min

While studies in mice indicate the potential direct benefits of GLP-1 on the skeletal muscle and bone, human data supporting this hypothesis are absent owing to the absence of GLP-1 receptors in the human skeletal muscle, implying that any effects on muscles are likely indirect [114]