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To signal, FGFs are released from the extracellular matrix by heparinases, proteases or specific FGF binding proteins, and the liberated FGFs subsequently bind to cell surface heparan sulphate proteoglycans (HPSGs) stabilizing the FGF-FGFR interaction [135]

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Depression and Emotional Numbness Interestingly, some individuals on Ozempic and Wegovy report experiencing emotional numbness - a sense of detachment from their feelings, relationships, or even personal achievements

But while many people expect some gastrointestinal discomfort on the meds, theres growing buzz about one scary side effect thats sparked several lawsuits: non-arteritic anterior ischemic optic neuropathy (NAION)

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