These species exist largely in a deprotonated anionic form at physiological pH, while most biothiols exist largely in a neutral protonated form (e.g., the p K a values of glutathione persulfide (GSSH) and glutathione (GSH) were reported to be 5.45 and 8.94, respectively) (Figure 1A) (Figure 1B) (Park et al., 2015)
A complete data set at 1.9 resolution was collected at beamline BL-5C of the Pohang Accelerator Laboratory (Pohang, Korea)
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Validation of this novel approach will lead to the design of new clinical trials using LC supplementation coupled with lower vitamin D doses as an adjuvant therapy to reduce 25(OH)VD deficiency/inadequacy and its associated complications and help reduce the related health hazards, particularly in the AA population
