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Gatan K3 direct electron detector positioned post a Gatan BioQuantum energy filter (Gatan, Pleasanton, California, USA), operated in a zero-loss mode with a slit width of 25 eV was used to acquire dose fractionated images of the samples with a 100 m objective aperture

Clinical studies have reported that berberine supplementation can lower liver lipid content and improve lipid profiles in patients with NAFLD

According to NICE Guidelines, GLP-1 medications such as semaglutide can be prescribed for weight management in certain patients when lifestyle changes alone have not been effective

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This has opened new avenues for treatment, as weight management is a critical component of overall health and can help mitigate the risk of developing other chronic conditions