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So glutamine was enough to sustain them

Compared to ROS induction by treatment with tert-butyl hydroperoxide (TBHP), an exogenous inducer of oxidative stress 37 , ROS levels were only slightly increased in PANC-1 cells and actually decreased MSTO-211H cells (Supplementary Fig

This synergy likely explains why tirzepatide produces substantially more weight loss than semaglutide despite both activating GLP-1 receptors

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Smith, B., & Olsson, H