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Research has shown GHK-Cu influences expression of over 4,000 human genes, stimulates collagen I, III and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, supports angiogenesis through VEGF and FGF upregulation, and suppresses pro-inflammatory TNF- signalling

acknowledges support from the NIH (R37CA240625, R01CA259111, R01CA298386, P30CA010815 and P30CA047904), the Sandy Rollman Ovarian Cancer Foundation, the American Cancer Society (RSG-19-113-01-CCG), the Congressionally Directed Medical Research Program (HT9425-23-1-0436), the UPMC Hillman Cancer Center and the Wistar Institute

EMBO Rep.16, 10711083 (2015)

If you have sensitive skin or underlying conditions, starting with less frequent treatments and monitoring your skins response is recommended

Research Insights: BPC157 is a synthetic peptide fragment derived from a naturally occurring protein segment, often studied for signaling pathways linked to tissue protection and blood vessel formation

Three further Phase 3 trial results in the TRIUMPH programme are due before the end of 2026: TRIUMPH-2 in obesity with type 2 diabetes, TRIUMPH-3 in obesity with established cardiovascular disease (with further safety information relevant to higher-risk populations), and obstructive sleep apnoea