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Multidrug resistance-associated protein-1 (MRP-1)-dependent glutathione disulfide (GSSG) efflux as a critical survival factor for oxidant-enriched tumorigenic endothelial cells

Glutathione in the Nervous System as a Potential Therapeutic Target to Control the Development and Progression of Amyotrophic Lateral Sclerosis Chatterjee, A

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To investigate whether the observed effects of individual transporters on metal toxicity were cell typespecific, we conducted the same validation experiments in an additional cell line

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It is unique because it can pass through the mitochondria and enter the nucleus of the cell, where it activates signals that promote normal metabolic homeostasis of glucose and lipid metabolism