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doi:10.1016/0048-9697(86)90018-5

Furthermore, it has been observed that hyperhomocysteinemia is often associated with endothelial dysfunction and inflammation, both of which are known to contribute to the development and progression of diabetic retinopathy

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In addition, the expression pattern of GPR146 closely resembled that of Pparg , suggesting a potential role for GPR146 in regulating adipogenesis (Supplementary Fig