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Nasal mucosal epithelial cells demonstrated reduced apoptotic marker expression including cleaved-CASP-3, cyt-c, NLRP3, ASC, IL-1, IL-18, CASP-1, and cleaved CASP-1, and increased Bcl-2, confirmed by TUNEL-positive apoptotic cell reduction, suggesting an inhibition of anti-apoptotic and anti-inflammatory effects on nasal tissue [219]