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Liposomal glutathione is encased in a protective layer of healthy fats (phospholipids) that allows it to survive the digestive process and be absorbed directly into the cells, resulting in much higher bioavailability.

One negative aspect of utilizing maleimide chemistry for cysteine linkage has been its chemical instability in plasma, including a retro-Michael reaction which results in premature loss of the drug-linker from the ADC

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