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A 2025 Phase I trial (Lee & Burgess, 2025) demonstrated that IV BPC-157 doses up to 20 mg were tolerated in healthy volunteers with no serious adverse events

Changes in glucose metabolism culminate in endothelial dysfunction and the activation of downstream inflammatory and pro-fibrotic pathways involving immune cell recruitment and TGF-1 production

Other studies demonstrated intravenous glutathione rapidly improved liver function, also evidenced by reduced biomarkers, in the treatment of other liver pathologies including chronic hepatitis B

BPC-157 has been prohibited by the World Anti-Doping Agency (WADA) since 2022 and is banned in many professional sports organizations

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