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High relative potency GLP-1 Influences appetite, fullness, energy intake, gastric emptying and glucose regulation

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Expert Opin Ther Pat (2020) 30:78194

Slowed gastric emptying caused by GLP-1 receptor activation means high-fat, fried, and ultra-processed foods are more likely to worsen nausea, bloating, and upper abdominal discomfort

Another 5% to 10% were low responders, losing less than 10% despite completing the full protocol

Nutritional therapies and herbs both improve GLP-1 activity and in many cases correct the numerous underlying contributors to metabolic dysfunction, through improving insulin sensitivity and satiety, supporting microbiome health and mitigating inflammation that can disrupt metabolic function