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Heart rate and blood pressure often normalize as well, offering cardiovascular benefits beyond weight loss

Slower stomach emptying means food or liquid may remain in your stomach longer, increasing aspiration risk if stomach contents are inhaled during intubation

The SURMOUNT-1 data shows continued, though modest, reductions even beyond one year

The COMBO-DN study was a large, double-blind, randomized clinical trial that compared the efficacy and safety of high-dose monotherapy versus combination therapy with duloxetine and pregabalin in patients with DPN who had not responded to standard doses [126]

Here are the key mechanisms: 1

Discuss your genetic predispositions, liver health, and lipid panel with your provider to frame a personalized plan