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Download the Notable Articles of 2025: nej.md/3L4ot87 In the phase 3 ACHIEVE-1 trial, published in June 2025, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes

Free radicals, stress, current lifestyle of young busy people, rush, and lack of physical activity expose our body to damage and accelerate the ageing process

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In April 2026, Nora Volkow and Xu reviewed reports of lower rates of alcohol-related events, reduced opioid overdose risk, and associations extending to nicotine, cocaine, cannabis, and other substances

(3) the DSNP's guidelines, expertise, and training approach for the SNP provider network

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