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Persistent, severe itching may indicate an underlying condition requiring investigation

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Triple-Hormone-Receptor Agonist Retatrutide for Obesity PubMed record (NCT04881760)

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Key findings include: Weight regain averaged 0.8 kg (1.8 lbs) per month after stopping injections Most participants returned to their starting weight within 18 months Regain was 0.3 kg per month faster than traditional dieting and exercise, regardless of initial weight loss The research highlights the importance of ongoing clinical oversight and behavioural support, as 9 in 10 UK users currently buy these drugs privately, often without NHS guidance