These agents include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro, Zepbound), which also targets the glucose-dependent insulinotropic polypeptide (GIP) receptor
A clinical trial published last month (called SURMOUNT-1) found many people taking tirzepatide for obesity lost a jaw-dropping 20% of their weight or even more
Most patients use 1 ml injections two to three times per week
The fasting plasma levels of GIP typically range between 10 20 pM with the peak values reaching around 80 150 pM after a meal (3336)
Its also thought to decrease appetite and increase satiety
As obesity-related diseases continue to pressure public health infrastructure, pharmaceuticals are exploring the potential use of these medicines in long-term chronic disease therapy