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Alpha Lipoic Acid (Thioctic Acid) Alpha Lipoic Acid is a potent antioxidant that eliminates free radicals and protects the skin from oxidative stress

PKLR is an enzyme responsible for catalyzing the conversion of phosphoenolpyruvate and adenosine triphosphate (ATP) to pyruvate and ATP in glycolysis 45

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In 2010, taVNS was approved in Europe for the treatment of epilepsy and depression, and in 2012, it was approved for the treatment of pain (117, 118)

Amplicons were sequenced to the same depth as the baseline libraries on Illumina MiSeq and NextSeq instruments in single-end format (100 bp) with two (8 bp) index reads