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In this context, GLP-1RAs are able to target six of these biological abnormalities, whereas other agents such as metformin target mainly one (Fig

Therefore, we suppose that other kinds of GLP-1R agonists, and high doses of GLP-1R agonists might have similar effects

These medications may slow the progression of osteoarthritis, not just through weight loss but by directly interacting with cells within the joint to slow the progression of the development of osteoarthritis, which is pretty profound, Heckmann said

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease

J Clin Oncol 33:195201