However, in contrast to untransformed human T-cells, in which SFN treatment led to a decrease of GSH, the GSH level in Jurkat T-leukemia cells showed a significant increase after 1 day of SFN treatment (Figure 4D)
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Cysteine is also essential for the ability of cancer cells to evade drug exposure and cell injury and adapt to other stressful conditions such as hypoxia
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Blood 100:765a, 2002