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Vitamin E also prevents the metabolism of 12-LOX, a key mediator of glutamate-induced neurodegeneration, by preventing arachidonic acid from entering the catalytic site of 12-LOX and enabling vitamin E to effectively prevent neuronal degeneration (Khanna et al., 2003)

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That distinction matters clinically, but it does not change the fact that NAD+ therapy is one of the most evidence-backed interventions we use for energy, cellular repair, and cognitive performance at our clinic

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