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Participants were not allowed to take any other supplements except a standard optional multivitamin offered by the trial team
Future research should investigate long-term outcomes in high-risk populations, direct comparisons between physiological and pharmacological dosages, cost-effectiveness analyses, and adherence metrics to inform optimal strategies for the prevention and management of vitamin B12 deficiency
Safe B12 Dosage and NHS Recommendations The NHS and UK health authorities provide clear guidance on appropriate vitamin B12 intake, emphasising that most people obtain sufficient amounts through diet alone
Unless otherwise prescribed by your doctor, the usual dose is: At the start of treatment, 1 ml (1 ampoule) is administered once or twice a week for the first two weeks after diagnosis, corresponding to 1000-2000 g of cyanocobalamin per week
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