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Diabetic retinopathy: 103 million patients, leading cause of working-age blindness

While we observed no autoproteolytic processing for recombinantly expressed and purified SnCE1 being acetylated at multiple lysine side chains, for SnCE1 C256A site-specifically acetylated at Lys78, Lys94, Lys98 (and Lys248) we observe an impaired SnCE1 autoproteolysis compared to non-acetylated SnCE1 C256A

Final eligibility is determined by the treating doctor after evaluating medical history, hydration status, risk factors, and overall treatment goals

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These findings underscore the importance of PTL composition in determining antimicrobial efficacy and suggest that tailoring RONS profiles to exploit specific weaknesses in bacterial antioxidant systems could enhance the efficacy of plasma-based treatments