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For general wellness maintenance, oral precursors like NAC or GlyNAC supplementation can modestly support endogenous synthesis, but they are not equivalent to IV administration for therapeutic replenishment

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J Biol Chem (2003) 278(29):2730111.10.1074/jbc.M302516200 113 Ben-AvrahamDGovindarajuDRBudagovTFradinDDurdaPLiuBet alThe GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature

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