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Related studies (10) have found that GLP-1RAs can inhibit the PI3K/AKT/mTOR and ERK/MAPK pathways, thereby inhibiting the growth of prostate cancer

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Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents

This means retatrutide activates the GIP receptor most aggressively, the GLP-1 receptor at moderate strength, and the glucagon receptor at the lowest level

People taking diabetes medications, especially insulin or sulfonylureas, should be monitored for possible low blood sugar when using therapies that affect glucose regulation