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This model using hCMEC/D3 favored ECD, by decreasing cell proliferation, increasing caspase 3/7 levels, inducing apoptosis, increasing oxidative phosphorylation, inducing mitochondrial dysfunction, and promoting higher cell migration [115]

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AKT, an effector molecule downstream of PI3K activation, is widely involved in the biological processes of the PI3K/AKT pathway

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doi: 10.1155/2017/2525967

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