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Serum IGF-1 monitoring at 6 to 8 week intervals provides the most reliable feedback on whether the protocol is producing the intended biological effect [19]

While these drugs have undeniably improved lives, the costs in terms of safety, access and ethical compromise are equally undeniable

Lancet HIV

Amin RH, Mathews ST, Camp HS, Ding L, Leff T

Arch Biochem Biophys 356:12732 Helbling B, von Overbeck J, Lauterburg BH (1996) Decreased release of glutathione into the systemic circulation of patients with HIV infection

MPNSTs frequently occur in patients with underlying genetic conditions, notably Neurofibromatosis type 1 (NF1) , where the lifetime risk of developing MPNST ranges from 813%