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The authors reported greater reductions in body weight and in glycated hemoglobin in the combination arm relative to either monotherapy arm within the trial, with gastrointestinal events again the most frequently reported category

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Gut microbiota in Parkinson disease in a northern German cohort

PT-141 (Bremelanotide) Primary focus: Female sexual dysfunction Hypoactive Sexual Desire Disorder (HSDD) PT-141 is the only peptide on this list with direct FDA approval for a women's health indication

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Therefore, testing for the MTHFR 1298 variant does not seem reasonable given the homozygous wild type status at position 677 (677CC)