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In TRIUMPH-1, discontinuation rates due to adverse events were 4.1% on 4 mg, 6.9% on 9 mg, and 11.3% on 12 mg, compared with 4.9% on placebo

Injecting outside approved sites or into areas with poor subcutaneous tissue, active skin conditions, or scar tissue may compromise medication delivery and increase infection risk

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doi: 10.3389/fmed.2022.875430 Summary Keywords glucagon-like peptide-1 receptor agonist (GLP-1RA), incretin based therapy, glucose-depent insulinotropic peptide (GIP), dual agonists, tirzepatide, type 2 diabetes Citation Gallwitz B (2022) Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity