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This lack of efficacy may be attributed to the low plasma and sputum concentrations of NTZ and the high plasma protein binding of tizoxanide, the active metabolite of NTZ [80], highlighting the need for further pharmacokinetic optimization and clinical research to better understand its potential role in TB treatment

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References For Further Reading (1) D.Gwyer, N.M.Wragg & S.L.Wilson (2019) Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing Cell and Tissue Research Volume 377, pages 153159, 27 March 2019