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103,104,105,106 However, a variety of stimuli, including nutrient perturbation, genotoxic stress, infection, pollutants and xenobiotics, trigger ROS overproduction, resulting in excessive oxidant challenge (oxidative distress)

CoQ10 levels are found to be even more deficient in people with certain health conditions and in those who take various medications, especially cholesterol-lowering drugs called statins

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While we don't have large IV studies yet, the biological rationale is rock-solidreplenishing glutathione could help break this destructive cycle