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Many patients find it frustrating to reach a hard-earned goal only to feel distracted by loose or uneven skin

The Negative Feedback Crossover (A Suppressive Effect) Remember those negative feedback loops

Promoting the regeneration and repair of skin cells can help improve skin damage caused by environmental factors such as ultraviolet radiation and pollution

Reported complications include gastroparesis, delayed gastric emptying, severe nausea, persistent vomiting, bowel obstruction, severe constipation, abdominal pain, dehydration, and other digestive-system injuries that may require hospitalization or long-term treatment

Guo S, Yao Q, Ke Z, Chen H, Wu J, Liu C

Reference Intake (RI*): 375 mg per day for adults (100% RI)