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Syn-RA16 had a high binding affinity (Kd ~ 24.75 nM), akin to the previously documented RA16 aptamer, and displayed dose-dependent suppression of cell viability, with IC50 values around 118.4 nM

This approach helps assess real-world use and adoption following regulatory approvals

Based on the above studies, we can find that SalB exhibits anti-HF properties by impeding HSC proliferation and activation as well as suppressing collagen accumulation through diverse mechanisms, including TGF, Wnt, PDGF, Hh, etc

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