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Too much homocysteine is strongly associated with an increased risk of heart disease.[ref] Related article: Homocysteine, genetics, and health Excess B12 and cancer growth: The other side of the picture, though, is that there may be times when limiting methionine is helpful , such as in fighting the proliferation of cancer cells

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Riboflavin is also a component of the glutathione redox cycle 24 , and lower riboflavin levels may lead to reduced glutathione

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This deceleration was particularly noticeable in the control group