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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Wang J

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In prior studies, it was found that these two classes of drugs showed heart and kidney benefits besides controlling blood sugar.[3] The researchers analyzed data from six previous trials of GLP-1 (including a total of 51,762 subjects) and four trials of SGLT2 inhibitors (including 33,457 subjects)

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Key Takeaways Injectable GLP-1s have significantly higher bioavailability than oral formulations, which can translate into stronger, more predictable clinical effects

Launching an oral IL-23 that competes with your own injectable looks risky on paper