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[DOI] [PubMed] [Google Scholar] 43.Newsome P.N., Sanyal A.J., Engebretsen K.A., Kliers I., Ostergaard L., Vanni D., Bugianesi E., Rinella M.E., Roden M., Ratziu V

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Gut microbiome links obesity to type 2 diabetes: insights from Mendelian randomization

177 Through enhancement of intestinal barrier function, modulation of microbial composition, and suppression of gut-derived inflammation, SIRT1 establishes a systemic regulatory framework at the gutliver axis level