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(Retatrutide discovery) Jastreboff AM, et al
These include orlistat, liraglutide, and semaglutide (NICE TA875 for weight management in adults with obesity), as well as GLP-1 receptor agonists within the framework of NICE NG28 (type 2 diabetes management)
Pyroptosis and subsequent inflammasome activation were evaluated by cleaved gasdermin D, cleaved caspase-1, and NLRP3, IL-1 and IL-18 expression
In summary, both menopause and perimenopause bring significant changes to the body, particularly concerning weight