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A plethora of studies have substantiated that dysregulation of zinc transporter proteins not only affects cell proliferation and apoptosis but also induces alterations in various signaling pathways, thus promoting cancer progression

We observed a negative correlation between Clostridium_sensu_stricto_1 and WithaferinA, JP83, bhos#36, 19-oxodesacetylcinobufagin, and (2s,4R,5R,6R,14S,16R)-14-Hydroxy-7,11-dimethyl-6-(2-OXOPYRAN-4-YL)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate

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The FDA did not approve AOD-9604 for therapeutic use, but the rejection was based on insufficient efficacy data for obesity treatment