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Su abordaje ha cambiado por completo desde que en 2008 apareci el primer agonista de GLP-1: se administraba dos veces al da e iba directamente al origen del problema metablico, el exceso de adiposidad" , resume Morales, que trabaja en el Hospital Universitario Virgen Macarena de Sevilla

351,352 The DNA oxidative damage and protein oxidation in the aged human brain are associated with declined antioxidant enzyme activities

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63,472,473 Beyond the metabolic activity, NAMPT may also participate in NAFLDs pathogenesis by controlling hepatic inflammation, insulin resistance and glucose homeostasis