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Miners et al

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Description What Is Glucagon-Like Peptide-1

According to their respective PK profiles, exenatide BID and lixisenatide can be categorized as short-acting agents (each has a half-life of 35 h) compared with the long-acting agents liraglutide, exenatide LAR, albiglutide, and dulaglutide, which have half-lives ranging from 12 h to several days [16]

Glucose is the principal precursor for GABA production via its conversion to -ketoglutarate in the TCA cycle