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The medication also slows gastric emptying, which prolongs the feeling of fullness after meals and helps moderate postprandial glucose excursions

Whilst Ozempic is licensed specifically for glycaemic control in type 2 diabetes, many patients experience weight loss as a secondary effect, typically in the range of 4-8% of body weight depending on dose

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In the past, researchers had to terminate studies on other drugs similar to orforglipron because of this effect