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Fatigue associated with Mounjaro is often temporary and may resolve as the body adjusts to the medication, says Shopana Ganpath, MD, an internist with IntraCare Health Center in Grapevine, Texas

However, if your hot flashes, night sweats, or other menopause symptoms suddenly return after starting a GLP-1, its worth discussing with your healthcare provider

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In contrast, a recent large registry cohort study by Ueda et al., which utilized data from nationwide registers in Sweden, Denmark, and Norway, found no difference in the risk of intestinal obstruction when comparing GLP-1RAs to SGLT2 inhibitors among over 300,000 patients [16]