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Kummel, D., Herrmann, E., Langemeyer, L

The peptides structure, composed of 15 amino acids, was designed to mimic the protective effects of the original protein, while also being stable enough for potential therapeutic use

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Given that GIP-mediated insulinotropic effects are diminished under chronic hyperglycemia [76, 77], the biased agonism of tirzepatide toward the GLP-1 receptor plays a crucial role in its efficacy