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Endogenous GLP-1 released from the gut acts directly on vagal afferents, which relay information from the abdomen to the brain and regulate multiple physiological systems

Theyre gonna slow down your digestion, theyre gonna make you feel full, and if you combine that with eating nutrient-dense foods that are more full of water and fiber and protein, youre gonna feel full on smaller amounts of food and youll lose more weight with the medication. And if youre close to the threshold but not over it

Your health care provider may also ask you to stop taking medicines that may affect the test, including pain medications like codeine, morphine, indomethacin, birth control pills, thiazide diuretics, cholinergic drugs and others

The result suggests that people with autism regulate these chemicals differently than typical individuals do

N Engl J Med 385(6):503515

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