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Kindelan, K

Scand J Plast Reconstr Surg 1973

Animal studies indicate fetal growth restriction, ossification delay, skeletal variants, and reduced maternal weight gain, though more recent human evidence, including a 2024 cohort of 938 pregnancies, suggests no increased risk of major congenital malformations compared with insulin

Risk factors for COVID-19 include cardiovascular disease and diabetes, and such high-risk groups exhibit common metabolic features of low levels of Gln, NAD + , and overproduction of hyaluronic acid (HA)

Oeltzschner G, Wijtenburg SA, Mikkelsen M, Edden RAE, Barker PB, Joo JH, et al